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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2209 | Serotonin hydrochloride | 5-HT hydrochloride,5-HT HCl,Serotonin HCl,5-Hydroxytryptamine hydrochloride | 5-HT Receptor , Endogenous Metabolite , Transferase |
Serotonin hydrochloride (Serotonin HCl) is an endogenous 5-HT receptor agonist, a monoamine neurotransmitter in the CNS, and a catechol O-methyltransferase (COMT) inhibitor(Ki=44 μM). | |||
T2688 | LY310762 | LY310762 HCl | 5-HT Receptor |
LY310762 is a 5-HT1D receptor antagonist with Ki of 249 nM. | |||
T0472 | Venlafaxine hydrochloride | Venlafaxine HCl,Wy 45030 hydrochloride | 5-HT Receptor , Serotonin Transporter |
Venlafaxine hydrochloride (Wy 45030 hydrochloride) is a cyclohexanol and phenylethylamine derivative that functions as a SEROTONIN AND NORADRENALINE REUPTAKE INHIBITOR (SNRI) and is used as an ANTIDEPRESSIVE AGENT. | |||
T6232 | Vilazodone Hydrochloride | SB659746A,EMD 68843,Vilazodone HCl | Others , 5-HT Receptor , Serotonin Transporter |
Vilazodone Hydrochloride (EMD 68843) , a partial agonist of 5-HT1A receptors and specific serotonin reuptake inhibitor (SSRI), is utilized in treating of the major depressive disorder. | |||
T0482 | Sertraline hydrochloride | Sertraline HCl,CP-51974-1 HCl | 5-HT Receptor , Serotonin Transporter |
Sertraline hydrochloride (Sertraline HCl) is a selective serotonin uptake inhibitor that is used in the treatment of depression. | |||
T21029 | Norfluoxetine Hydrochloride | Norfluoxetine HCl | Others |
Norfluoxetine Hydrochloride (Norfluoxetine HCl) is an active metabolite of fluoxetine. Fluoxetine is an antidepressant drug. | |||
T0088 | Urapidil hydrochloride | Urapidil HCl | 5-HT Receptor , Adrenergic Receptor |
Urapidil hydrochloride (Urapidil HCl) is 5-HT1A receptor agonist and an α1-adrenoceptor antagonist. | |||
T1189 | Milnacipran hydrochloride | Milnacipran HCl,Savella,Dalcipran | Serotonin Transporter , Norepinephrine |
Milnacipran hydrochloride (Savella) is a serotonin and norepinephrine reuptake inhibitor used to treat major depressive disorders. Milnacipran hydrochloride is an enantiomer of milnacipran, which is used to treat fibromy... | |||
T1042 | Granisetron hydrochloride | BRL 43694A,Granisetron HCl | 5-HT Receptor |
Granisetron hydrochloride (Granisetron HCl) is a serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic for cancer chemotherapy patients. | |||
T1528 | Azasetron hydrochloride | Y-25130 hydrochloride,Y-25130 HCl,Azasetron HCl | 5-HT Receptor |
Azasetron hydrochloride (Y-25130 HCl) is a 5-HT3 receptor antagonist which is used as an anti-emetic. | |||
T1069 | Metoclopramide hydrochloride | Maxolon,Metoclopramide HCl | Dopamine Receptor , 5-HT Receptor , AChR |
Metoclopramide hydrochloride (Metoclopramide HCl) is a selective dopamine D2 receptor antagonist, used as an antiemetic. | |||
T6655 | SB-269970 hydrochloride | SB-269970A,SB269970 HCl | 5-HT Receptor |
SB-269970 hydrochloride (SB-269970A) , a hydrochloride salt form of SB-269970, is a 5-HT7 receptor antagonist (pKi of 8.3) and exhibits >50-fold selectivity against other receptors. | |||
T0450L | Fluoxetine hydrochloride | Fluoxetine HCl,LY-110140,Lilly110140 | 5-HT Receptor , Serotonin Transporter , Autophagy |
Fluoxetine hydrochloride (Lilly110140) is the first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants. | |||
T6461 | Dapoxetine hydrochloride | LY-210448,LY-210448 hydrochloride,Dapoxetine HCl,Priligy | 5-HT Receptor , Serotonin Transporter |
Dapoxetine hydrochloride (LY-210448 hydrochloride) is a selectivity short-acting serotonin reuptake inhibitor, used for the therapy of premature ejaculation. | |||
T2132 | Buspirone hydrochloride | Buspirone HCl,Narol,Buspar | Dopamine Receptor , 5-HT Receptor |
Buspirone hydrochloride (Buspar) is a 5HT(1A) receptor agonist, used to treat generalized anxiety disorder (GAD). | |||
T1509 | Cyclobenzaprine hydrochloride | Cyclobenzaprine HCl,MK130 hydrochloride | 5-HT Receptor |
Cyclobenzaprine hydrochloride (MK130 hydrochloride) , a centrally acting muscle relaxant with antidepressant activity, leads to a reduction in muscle spasms. | |||
T7941 | Imipramine hydrochloride | Imipramine (hydrochloride),Tofranil,G 22355,Imipramine HCl,Melipramine | Serotonin Transporter |
Imipramine hydrochloride (Imipramine HCl) is a first generation tricyclic antidepressant that acts primarily as an inhibitor of serotonin and norepinephrine transporters (Kds = 1.4 and 37 nM, respectively).Imipramine hyd... | |||
T6814 | Cyproheptadine hydrochloride | Periactin hydrochloride,Anarexol,Cyproheptadine HCl,Nuran | 5-HT Receptor |
Cyproheptadine hydrochloride (Periactin hydrochloride) is a hydrochloride salt form of cyproheptadine which is a histamine receptor antagonist. | |||
T1156 | Palonosetron hydrochloride | RS 25259 197,Palonosetron HCl,RS 25259 | 5-HT Receptor |
Palonosetron hydrochloride (RS 25259) is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting. | |||
T8382 | Cariprazine hydrochloride | Cariprazine HCl,RGH188 hydrochloride | Dopamine Receptor , 5-HT Receptor |
Cariprazine hydrochloride (RGH188 hydrochloride) is an antipsychotic drug, is a D3 and D2 receptor partial agonist((Ki of 0.085 nM and 0.49 nM, respectively) |